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Elements of Clinical Research in Psychiatry

James E. Mitchell, M.D., Ross D. Crosby, Ph.D., Stephen A. Wonderlich, Ph.D., and David E. Adson, M.D.

  • ISBN 978-0-88048-802-0
  • Item #8802

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Description

Clinical research is often thought of as a dry and somewhat arcane pursuit.

Not so, assert the editors of Elements of Clinical Research in Psychiatry. The editors, all actively engaged in clinical research, bring this topic to life by combining a boundless enthusiasm for their chosen field with a depth of knowledge rarely seen in the literature. They show that clinical research can be rewarding not only because the research results contribute to improving the welfare of psychiatric patients, but also because the research process itself is exciting.

Arguably the definitive guidebook on clinical psychiatric research, this volume discusses

  • Careers in clinical mental health research—Describes what clinical psychiatric researchers do and how to get started on this career path.

  • Research design, measurement, and assessment—Covers all aspects of research design, defines and evaluates measurement types, and details various assessment methods (from interviews and questionnaires to lab tests and brain images).

  • Descriptive and inferential statistics—Shows how statistics are used to analyze and summarize measurement data.

  • Research support—Provides a roadmap for those seeking research support in the U.S. (more than 90% is funded via NIH), detailing how to write grants from the ground up.

  • Use of human subjects (the Institutional Review Board [IRB]) and ethics and misconduct—Demystifies the often intimidating process of seeking and receiving IRB approval, with tips on how to work with the IRB and complete its consent forms; uses a series of practical scenarios, including a highly publicized case of alleged misconduct, to illustrate complex ethics and misconduct issues.

  • Writing journal articles, reviewing manuscripts, and giving scientific presentations—Presents the nuts and bolts of publishing journal articles; gives step-by-step advice for reviewing manuscripts and giving oral presentations, symposia, poster sessions, and colloquia.

Carefully chosen appendixes provide readers with additional information they can use right away, augmented by an index and detailed reference list for further investigation.

Anyone considering clinical psychiatric research as a career option will find in this succinct and eminently practical volume the single source they need. Practicing psychiatrists interested in specific areas of clinical research, such as human subject use or biomedical ethics, will also find much of interest here. Replete with useful information, these stimulating discussions provide the building blocks for embarking upon—and enhancing—a successful career in clinical psychiatric research.

Contents

  • About the Authors
  • Introduction
  • Chapter 1. Careers in Clinical Mental Health Research
  • Chapter 2. Research Design
  • Chapter 3. Measurement
  • Chapter 4. Assessment
  • Chapter 5. Descriptive Statistics
  • Chapter 6. Inferential Statistics
  • Chapter 7. Research Support
  • Chapter 8. Use of Human Subjects in Research: The Institutional Review Board
  • Chapter 9. Ethics and Misconduct
  • Chapter 10. Writing Journal Articles
  • Chapter 11. Reviewing Journal Articles
  • Chapter 12. Scientific Presentations
  • Appendixes:
  • A: The Nuremberg Code
  • B: World Medical Association Declaration of Helsinki
  • C: Research Involving the U.S. Food and Drug Administration
  • D: Scales and Questionnaires for the Diagnosis and Assessment of Psychiatric Disorders in Clinical Psychiatric Research
  • E: Web Sites: Resources for Research and Ethics
  • F: Contacts and Telephone Numbers at the National Institutes of Health
  • G: National Institutes of Health Grant Application Reviews (NIH)
  • References
  • Index

About the Authors

James E. Mitchell, M.D., is President and Scientific Director of the Neuropsychiatric Research Institute and Professor and Chairman of the Department of Neurosciences at the University of North Dakota School of Medicine and Health Sciences in Fargo, North Dakota.

Ross D. Crosby, Ph.D., is Director of Methodology and Statistics of the Neuropsychiatric Research Institute and Associate Professor in the Department of Neurosciences at the University of North Dakota School of Medicine and Health Sciences in Fargo, North Dakota.

Stephen A. Wonderlich, Ph.D., is Director of Clinical Research at the Neuropsychiatric Research Institute and Professor and Associate Chair of the Department of Neurosciences at the University of North Dakota School of Medicine and Health Sciences in Fargo, North Dakota.

David E. Adson, M.D., is Assistant Professor of Psychiatry at the University of Minnesota Medical School and Chair of a Medical Panel of the Institutional Review Board (IRB) at the University of Minnesota in Minneapolis, Minnesota.

This book is a must-read for anyone thinking of a career in clinical research. It should also be useful for other psychiatric trainees, not only to gain a better understanding of the field but also to understand the process in which their patients may be participating if they are subjects in clinical research.—Jayendra Patel, M.D., Psychiatric Services, 4/1/2002


It is an excellent 'must-buy' for those embarking on clinical research and a refreshing review for experienced researchers . . . Highly recommended.—Journal of Clinical Psychiatry 62:8, 4/1/2002

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