The American Psychiatric Association Publishing Textbook of Mood Disorders, Second Edition

Edited by Charles B. Nemeroff, M.D., Ph.D., Alan F. Schatzberg, M.D., Natalie Rasgon, M.D., Ph.D., and Stephen M. Strakowski, M.D.

2022
986 Pages
Editorial Reviews

ISBN 978-1-61537-331-4
Item #37331

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Description
Contents
Editorial Reviews
Contributors
About the Authors

This new edition of The American Psychiatric Association Publishing Textbook of Mood Disorders is a systematic and painstaking reconceptualization of its predecessor. Under new editorial direction and with a revised roster of expert contributors, the second edition is an utterly current, clinically competent, and comprehensive text that will become an instant classic. The book is structured for learning and easy reference, moving deftly from symptomatology and epidemiology to pathogenesis and on to somatic interventions, cognitive-behavioral interventions, and psychotherapy. The latest science on genetics and epigenetics, brain imaging, and neurobiology are also examined in depth. Critically important to the clinician is the section on management of mood disorders, which provides treatment guidelines for major depressive disorder and bipolar disorder, as well as information on understanding, and preventing, suicide in children, adolescents, and adults. Finally, perspectives are offered on depression among women, children, and geriatric patients, as well as on depression across cultures. Practicing psychiatrists, residents, and students alike will benefit from the book's inclusive coverage.

Topics new to this edition include the following:

Treatment-resistant depression—its definition and approaches to its treatment—is addressed in a dedicated chapter that covers diagnostic accuracy, pseudoresistance, comorbidity, pharmacological management, adjunctive strategies, psychotherapy, neuromodulation, and novel and experimental therapies.
Investigational agents, most notably ketamine and its relatives, constitute an exciting frontier in the treatment of mood disorders, and the clinical application, routes of delivery, dosing, risks, and clinical trials are explored in a dedicated chapter that is both rigorous and thorough.
There is compelling evidence that childhood maltreatment (defined as exposure to emotional, physical, and sexual abuse and neglect before the age of 18 years) is a prominent risk factor for the development of mood disorders as well as for a pernicious course and poor treatment response in mood disorders. These findings, as well as the underlying neurobiological and environmental interactions that may contribute to the development of mood disorders, are examined thoroughly and thoughtfully.
As our understanding of immune function in mood disorders has grown, psychoneuroimmunology has emerged as a focus of study likely to make major contributions to clinical practice in the coming decades. The book updates readers on this promising area of research.

Over the last decade, depression has emerged as the leading cause of disability worldwide, with significant attendant morbidity and mortality. The American Psychiatric Association Publishing Textbook of Mood Disorders equips clinicians and trainees with the knowledge they need to alleviate suffering in their patients with mood disorders.

Contributors
Preface
Part I: Symptomatology and Epidemiology
Chapter 1. Historical Aspects of Mood Disorders
Chapter 2. Classifications of Mood Disorders
Chapter 3. The Epidemiology and Burdens of Mood Disorders
Chapter 4. Rating Scales and Structured Diagnostic Interviews for Mood Disorders
Part II: Pathogenesis of Mood Disorders
Chapter 5. Neurochemistry of Mood Disorders
Chapter 6. Psychoneuroendocrinology of Mood Disorders
Chapter 7. Role of the Immune System in Mood Disorders
Chapter 8. Evolutionary Contributions to the Understanding of Mood and Mood Disorders
Part III: Investigating Mood Disorders
Chapter 9. Anatomical Pathology
Chapter 10. Molecular and Cellular Neurobiology of Severe Mood Disorders
Chapter 11. Brain Imaging
Chapter 12. Review of Mood Disorder Genetics
Chapter 13. Epigenetics of Mood Disorders
Part IV: Somatic Interventions for Mood Disorders
Chapter 14. Tricyclics, Tetracyclics, and Monoamine Oxidase Inhibitors
Chapter 15. Selective Serotonin Reuptake Inhibitors, Serotonin-Norepinephrine Reuptake Inhibitors, and Other Related Antidepressants
Chapter 16. Lithium and Mood Stabilizers
Chapter 17. Use of Antipsychotic Medications in Mood Disorders
Chapter 18. Electroconvulsive Therapy in the Treatment of Mood Disorders
Chapter 19. Transcranial Magnetic Stimulation for Major Depressive Disorder
Chapter 20. Vagus Nerve Stimulation and Deep Brain Stimulation
Chapter 21. Other Antidepressants: Trazadone, Mirtazapine, Bupropion
Chapter 22. Ketamine and Other Investigational Agents
Part V: Psychotherapy of Mood Disorders
Chapter 23. Cognitive and Behavior Therapies for Major Depressive Disorder and Persistent Depressive Disorder
Chapter 24. Interpersonal Psychotherapy for Major Depressive Disorder and Persistent Depressive Disorder
Chapter 25. Psychoanalytic and Psychodynamic Psychotherapy for Depression and Dysthymia
Chapter 26. Psychotherapeutic Approaches to Bipolar Disorder
Chapter 27. Psychotherapy for Depression in Children and Adolescents
Part VI: Integrative Management of Mood Disorders
Chapter 28. Practice Guidelines for Major Depressive Disorder
Chapter 29. Guidelines for Treatment of Bipolar Disorder
Chapter 30. Understanding and Preventing Suicide
Chapter 31. Suicide in Children and Adolescents
Chapter 32. Combination Strategies for the Pharmacological Treatment of Major Depressive Disorder
Chapter 33. Management of Treatment-Resistant Depression
Part VII: Subtypes of Mood Disorders
Chapter 34. Seasonal Affective Disorder and Light Therapy for Mood Disorders
Chapter 35. Atypical Depression, Dysthymia, and Cyclothymia
Chapter 36. Major Depressive Disorder With Psychotic Features
Chapter 37. Pediatric Mood Disorders
Chapter 38. Geriatric Mood Disorders
Part VIII: Additional Perspectives on Mood Disorder
Chapter 39. Depression in Primary Care
Chapter 40. Depression in Medical Illness
Chapter 41. Mood Disorders and Substance Use
Chapter 42. Depression in Women
Chapter 43. Depression Across Cultures: An Ecosocial Approach
Chapter 44. Mood Disorders and Sleep
Chapter 45. Childhood Maltreatment and Mood Disorders
Index

Charles B. Nemeroff, M.D., Ph.D., is the Matthew P. Nemeroff Professor and Chair of the Department of Psychiatry & Behavioral Sciences at the University of Texas, Austin, Dell Medical School.

Natalie Rasgon, M.D., Ph.D., is a Professor in the Department of Psychiatry and Behavioral Sciences and Obstetrics and Gynecology at Stanford University School of Medicine and is also the Director of the Stanford Center for Neuroscience in Women's Health and the Associate Dean of Academic Affairs.

Alan F. Schatzberg, M.D., is Kenneth T. Norris, Jr., Professor in the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine in Stanford, California, where from 1991 to 2010 he was also the Chair of Psychiatry. He is currently Director of the Stanford Mood Disorders Center.

Stephen M. Strakowski, M.D., is Vice Dean of Research and Associate Vice President, Regional Mental Health, at the Dell Medical School, University of Texas at Austin. He is also Professor of Psychiatry & Behavioral Sciences, Psychology, and Educational Psychology at the University of Texas, Austin.

The Textbook of Mood Disorders, Second Edition provides a comprehensive and detailed resource for understanding the presentation, biology and treatment of affective ilnesses across the lifespan and across populations. Authors synthesize useful and accessable information to guide both seasoned and novice psychiatric clinicians in when approaching patients with depression and bipolar disorders. I strongly recommend this text for anyone who needs an easy to read, up to date one stop shop for questions related to treating patients with mood disorders.—Steven Siegel, M.D., Ph.D., Chair and Chief of Clinical Services, Department of Psychiatry and the Behavioral Sciences, Franz Alexander Endowed Chair in Psychiatry, Professor of Psychiatry and the Behavioral Sciences and Population and Public Health Sciences, Keck School of MedicineChief Mental Health and Wellness Officer, Keck Medicine of USCUniversity of Southern California