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Biology of Personality Disorders

Edited by Kenneth R. Silk, M.D.
Series Editors: John M. Oldham, M.D., M.S., and Michelle B. Riba, M.D., M.S.

  • ISBN 978-0-88048-835-8
  • Item #8835

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Edited by Kenneth R. Silk, this work is an all-inclusive guide for the study of the etiology and the treatment of personality disorders. Some of the outstanding features of this text are:

  • Two chapters devoted to the cutting edge research neurotransmitters and neuroimaging and discussion of future applications of these studies.
  • A complete examination of the Cloninger model of personality supported by independent tests and clinical samples.
  • New pharmacological treatment options based upon measurable behavioral targets.
  • A thorough comparison of genetic predisposition and psychosocial factors and a corresponding model for treatment.

For the many patients who suffer from personality disorders and the physicians who have the challenge of successfully treating them, this book is a welcome reference. Through examination of the biology of the disorders and better options for treatment, the Biology of Personality Disorders will be an excellent addition to your academic library.


  • Introduction to the review of psychiatry series. Neurotransmitter function in personality disorders. New biological researcher strategies for personality disorders. The genetics and psychobiology of the seven-factor model of personality. Psychopharmacological management of personality disorders: an outcome focused model. Significance of biological research for a biopsychosocial model of personality disorders.

About the Authors

Kenneth R. Silk, M.D., is Associate Professor and Chief of Adult Services and Director of the Personality Disorders Program of the Department of Psychiatry at The University of Michigan in Ann Arbor.

Comprehensive and current references accompanying each chapter are very helpful. The entire monograph is essential for personality theorists and researchers, as well as psychopathologists.—Readings: A Journal of Reviews and Commentary in Mental Health

The Biology of Personality Disorders, edited by Dr. Kenneth Silk, is a tremendous service to the theory, research, and treatment of personality disorders, as it goes far in dispelling the problematic and misleading stereotype of personality disorders as being nonbiological in etiology, pathology, and treatment. Dr. Silk has also brought together not only the best minds for the purpose, but the authors have lived up to the high expectations of their outstanding reputations. This text should be must reading for theorists, researchers, and practicing clinicians with any interest in personality disorders or biological models of psychopathology.—Thomas A. Widiger, Ph.D., Professor of Psychology, University of Kentucky, Associate Editor, Journal of Personality Disorders, Lexington, Kentucky

This ambitious book provides diverse perspectives on a new area of integrative research and theory. In chapters ranging from neurotransmitter studies to conceptual models to treatment implications, the authors make it clear how much we have learned in the last decade and how much is left to be done. This book makes a persuasive case for the importance of this line of research.—Donald F. Klein, M.D., Director, Psychiatry Research, Office of Mental Health, New York State Psychiatric Institute, New York, New York

This slim volume is mostly succinct and well-written. . . . I would recommend it as an excellent reference source for psychiatrists interested in research in the area.—Irish Journal of Psychological Medicine

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