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Current Treatments of Obsessive-Compulsive Disorder, Second Edition

Edited by Michele Tortora Pato, M.D., and Joseph Zohar, M.D.

  • ISBN 978-1-58562-801-8
  • Item #62801

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During the 10 years since publication of the first edition of this comprehensive volume, progress in neuroscience has had direct and immediate clinical implications in both the pharmacological and psychological arenas in the treatment of one of psychiatry's greatest challenges: obsessive-compulsive disorder (OCD).

This second edition reflects this progress. Chapters include the latest data on the use of all current OCD treatments in special populations, such as the strictly religious, the elderly, children, adolescents, and those who are pregnant, and all are illustrated with new and updated detailed case histories that highlight specific treatments and diagnostic issues. This edition includes

  • Three new pharmacotherapy chapters that discuss the use of sertraline, paroxetine, and citalopram and updates of the original edition's chapters on clomipramine, fluoxetine, and fluvoxamine
  • An expanded chapter on children and adolescents that emphasizes the benefits of early detection, and describes the latest findings in immunological research with particular regard to pediatric autoimmune neurologic disorders associated with streptococcal infection (PANDAS)
  • An expanded behavioral therapy chapter that encompasses not only detailed treatment plans for both individuals and groups (including multifamily groups) but also up-to-date empirical data to support their use
  • The latest data on compounds for treating OCD (twice the number of compounds are now available than when the first edition was published), including details of the dramatic increase in our knowledge of pharmacokinetics, receptor profiles, interactions, and comparative efficacy during the past decade
  • The clinical implications of today's broadened definition of OCD, which includes disorders such as body dysmorphic disorder, trichotillomania, pathological gambling, and Tourette's syndrome, and the complicated diagnostic and management issues—with a call for innovative treatment approaches—raised by the intimate relationship between OCD and schizophrenia (15% of patients with schizophrenia also have OCD)
  • A multidisciplinary approach to treatment-resistant OCD, which occurs in approximately 30% of all cases, suggesting ways to combine our current knowledge and focus it on the treatment of a specific individual

With their extensive clinical and research experience in treating OCD, the distinguished contributors to this volume provide clinicians with the latest, most reliable data so that they may better match treatment approaches with each patient's unique needs. Of enduring practical value, this updated how to manual will be welcomed by all clinicians treating patients with OCD, as well as students and other interested clinicians, as an effective tool in the ongoing challenge to understand and treat this frustrating disorder.


  • Contributors
  • Preface to the Second Edition
  • Chapter 1. General Considerations in Diagnosis and Treatment
  • Chapter 2. Clomipramine
  • Chapter 3. Fluoxetine
  • Chapter 4. Fluvoxamine
  • Chapter 5. Sertraline
  • Chapter 6. Paroxetine
  • Chapter 7. Citalopram
  • Chapter 8. Diagnosis and Treatment in Children and Adolescents
  • Chapter 9. Individual, Group, and Multifamily Cognitive-Behavioral Treatments
  • Chapter 10. Treatment of Strictly Religious Patients
  • Chapter 11. Serotonergic Drugs and the Treatment of Disorders Related to Obsessive-Compulsive Disorder
  • Chapter 12. Management of Treatment-Resistant Obsessive-Compulsive Disorder
  • Index

About the Authors

Michele Tortora Pato, M.D., is Associate Professor in the Department of Psychiatry and Director of Obsessive-Compulsive Disorder Research and Treatment Program at State University of New York at Buffalo located in Buffalo, NY.

Joseph Zohar, M.D., is Director for the Department of Psychiatry at Sheba Medical Center inTel Hashomer, Israel. Dr. Zohar is also an Associate Professor at the Sackler School of Medicine for Tel Aviv University in Tel Aviv, Israel.

The text beautifully straddles the fine line between providing useful information for those who suffer from OCD and for those who treat patients with OCD. As such, this book will be immensely valuable for patients and clinicians . . . The chapter on children and adolescents is an outstanding summary of current knowledge in the field . . . Drs. Pato and Zohar have accomplished that rare feat—compiling a text that is valuable for both those who suffer from an illness and for those who care for them. This text will most likely be an important resource for many years to come.—OCD Newsletter, 11/1/2002

This is an excellent review of OCD, and this second edition is certainly needed, due to the advent of SSRIs in treating this condition . . . This book is recommended reading for any practicing psychiatrist.—Doody Publishing, 11/1/2002

Overall, this is an extremely thoughtful, generally well-written, and clinically helpful updating of a useful guide for the perplexed.—Aaron H. Esman M.D., American Journal of Psychiatry, 11/1/2002

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