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The American Psychiatric Publishing Textbook of Mood Disorders

Edited by Dan J. Stein, M.D., Ph.D., David J. Kupfer, M.D., and Alan F. Schatzberg, M.D.

  • ISBN 978-1-58562-151-4
  • Item #62151

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Psychiatrists and other mental health care and medical professionals can now turn to a truly authoritative, up-to-date reference for current information about mood disorders. The American Psychiatric Publishing Textbook of Mood Disorders—including a wealth of illustrations, tables and references—presents the state of the art in diagnosis, psychobiology, pharmacotherapy, and psychotherapy across the vast spectrum of mood disorders:

  • Symptomatology and Epidemiology: historical aspects and social underpinnings of mood disorders, classification and rating scales, and global burden
  • Pathogenesis: neurochemistry and psychoneuroendocrinology, cognitive processing models (experimental cognitive research), and evolutionary explanations
  • Methods of Investigation:anatomical pathology, molecular and cellular neurobiology of severe mood disorders, and genetics of bipolar and unipolar disorders
  • Types of Mood Disorder: psychotic depression, seasonal affective disorder, secondary depression with medical illness, major depression seen in primary care, and substance abuse, and sleep disorders
  • Treatments: pharmacotherapy, brain stimulation techniques, and psychotherapies
  • Pertinent Factors: personality, culture, and gender

Offering a fascinating synthesis of the multifaceted field of mood disorders, the richly informative American Psychiatric Publishing Textbook of Mood Disorders will prove invaluable for psychiatric and medical practitioners, educators, students, and residents interested in the latest breakthroughs in the diagnosis, treatment, and management of mood disorders.


  • Contributors
  • Preface
  • PART 1: Symptomatology and Epidemiology
  • Chapter 1. Historical Aspects of Mood Disorders
  • Chapter 2. Classification of Mood Disorders
  • Chapter 3. Epidemiology of Mood Disorders
  • Chapter 4. Global Burden of Mood Disorders
  • Chapter 5. Rating Scales for Mood Disorders
  • PART 2: Pathogenesis of Mood Disorders
  • Chapter 6. Neurochemistry of Mood Disorders
  • Chapter 7. Psychoneuroendocrinology of Mood Disorders
  • Chapter 8. Cognitive Processing Models of Depression
  • Chapter 9. Social Perspectives on Mood Disorders
  • Chapter 10. Evolutionary Explanations for Mood and Mood Disorders
  • PART 3: Investigating Mood Disorders
  • Chapter 11. Anatomical Pathology
  • Chapter 12. Molecular and Cellular Neurobiology of Severe Mood Disorders
  • Chapter 13. Brain Imaging
  • Chapter 14. Genetics of Bipolar and Unipolar Disorders
  • PART 4: Somatic Interventions for Mood Disorders
  • Chapter 15. Tricyclics, Tetracyclics, and Monoamine Oxidase Inhibitors
  • Chapter 16. Selective Serotonin Reuptake Inhibitors and Newer Antidepressants
  • Chapter 17. Lithium and Mood Stabilizers
  • Chapter 18. Antipsychotic Medications
  • Chapter 19. Targeting Peptide and Hormonal Systems
  • Chapter 20. Electroconvulsive Therapy and Transcranial Magnetic Stimulation
  • Chapter 21. Vagus Nerve Stimulation and Deep Brain Stimulation
  • PART 5: Psychotherapy of Mood Disorders
  • Chapter 22. Cognitive-Behavioral Therapy for Depression and Dysthymia
  • Chapter 23. Interpersonal Psychotherapy for Depression and Dysthymic Disorder
  • Chapter 24. Psychoanalytic and Psychodynamic Psychotherapy for Depression and Dysthymia
  • Chapter 25. Psychotherapy for Bipolar Disorder
  • Chapter 26. Psychotherapy for Depression in Children and Adolescents
  • PART 6: Integrative Management of Mood Disorders
  • Chapter 27. Guidelines for the Treatment of Major Depression
  • Chapter 28. Guidelines for the Treatment of Bipolar Disorder
  • Chapter 29. Understanding and Preventing Suicide
  • Chapter 30. Suicide in Children and Adolescents
  • Chapter 31. Medication Combination and Augmentation Strategies in the Treatment of Major Depression
  • PART 7: Subtypes of Mood Disorders
  • Chapter 32. Seasonal Affective Disorder
  • Chapter 33. Atypical Depression, Dysthymia, and Cyclothymia
  • Chapter 34. Psychotic Depression
  • Chapter 35. Pediatric Mood Disorders
  • Chapter 36. Geriatric Mood Disorders
  • PART 8: Additional Perspective on Mood Disorders
  • Chapter 37. Depression in Primary Care
  • Chapter 38. Depression in Medical Illness (Secondary Depression)
  • Chapter 39. Mood Disorders and Substance Use
  • Chapter 40. Depression and Personality
  • Chapter 41. Depression and Gender
  • Chapter 42. Depression Across Cultures
  • Chapter 43. Mood Disorders and Sleep
  • Index


    Berry Anderson, R.N.
    Tanya J. Bennett, M.D.
    Susan Bentley, D.O.
    Wade Berrettini, M.D., Ph.D.
    Antje Bittner, Dipl.Psych.
    Pierre Blier, M.D., Ph.D.
    Daryl E. Bohning, Ph.D.
    Robert Boland, M.D.
    Jeffrey Borckardt, Ph.D.
    David A. Brent, M.D.
    Daniel J. Buysse, M.D.
    Joseph R. Calabrese, M.D.
    Colleen E. Carney, Ph.D., C.Psych.
    Kenneth Carpenter, Ph.D.
    Bruce K. Christensen, Ph.D., C.Psych.
    Dianne Currier, Ph.D.
    Carrie Davies, B.A.
    Pedro L. Delgado, M.D.
    D. P. Devanand, M.D.
    Mary Amanda Dew, Ph.D.
    Andrea F. DiMartini, M.D.
    Graham J. Emslie, M.D.
    Benjamin H. Flores, M.D.
    Ellen Frank, Ph.D.
    Edward S. Friedman, M.D.
    Glen O. Gabbard, M.D.
    Mark S. George, M.D.
    Anne Germain, Ph.D.
    Renee D. Goodwin, Ph.D., M.P.H.
    Todd D. Gould, M.D.
    Deborah Hasin, Ph.D.
    Jennifer L. Hughes, B.A.
    Frank Jacobi, Ph.D.
    G. Eric Jarvis, M.D., M.Sc.
    Wayne J. Katon, M.D.
    Paul E. Keck Jr., M.D.
    Beth D. Kennard, Psy.D.
    Ronald C. Kessler, Ph.D.
    Laurence J. Kirmayer, M.D.
    Daniel N. Klein, Ph.D.
    Susan G. Kornstein, M.D.
    F. Andrew Kozel, M.D., M.S.
    K. Ranga Rama Krishnan, M.B., Ch.B.
    David J. Kupfer, M.D.
    Natalie Lester, B.S.
    Xiangbao Li, M.D.
    J. John Mann, M.D.
    Husseini K. Manji, M.D.
    John C. Markowitz, M.D.
    Helen S. Mayberg, M.D.
    Taryn L. Mayes, M.S.
    Meghan E. McDevitt-Murphy, Ph.D.
    Susan L. McElroy, M.D.
    Brian R. McFarland, M.A.
    Francisco A. Moreno, M.D.
    Chiwen Mu, M.D., Ph.D.
    David J. Muzina, M.D.
    Larissa Myaskovsky, Ph.D.
    Ziad Nahas, M.D.
    Harold W. Neighbors, Ph.D.
    Randolph M. Nesse, M.D.
    Mitchell S. Nobler, M.D.
    Eric A. Nofzinger, M.D.
    Edward Nunes, M.D.
    Robert A. Padich, Ph.D.
    Cynthia R. Pfeffer, M.D.
    William Zeigler Potter, M.D. Ph.D.
    Jorge A. Quiroz, M.D.
    Frederic M. Quitkin, M.D., D.Sci.
    Grazyna Rajkowska, Ph.D.
    Steven P. Roose, M.D.
    Joshua Z. Rosenthal, M.D.
    Norman E. Rosenthal, M.D.
    Eric Rubin, M.D, Ph.D.
    Matthew V. Rudorfer, M.D.
    A. John Rush, M.D.
    Harold A. Sackeim, Ph.D.
    Alan F. Schatzberg, M.D.
    Zindel V. Segal, Ph.D., C.Psych.
    Stuart N. Seidman, M.D.
    Stewart A. Shankman, Ph.D.
    Richard C. Shelton, M.D.
    Jaskaran B. Singh, M.D.
    Diane M. E. Sloan, Pharm.D.
    M. Tracie Shea, Ph.D.
    Jonathan W. Stewart, M.D.
    Stephen M. Strakowski, M.D.
    Michael H. Stone, M.D.
    Holly A. Swartz, M.D.
    Galen E. Switzer, Ph.D.
    Michael E. Thase, M.D.
    Marianna I. Tovt-Korshynska, M.D., Ph.D.
    Philip S. Wang, M.D., Dr.P.H.
    V. Robin Weersing, Ph.D.
    David R. Williams, Ph.D., M.P.H.
    Hans-Ulrich Wittchen, Ph.D.
    Shirley Yen, Ph.D.
    Carlos A. Zarate, M.D.

About the Authors

Dan J. Stein, M.D., Ph.D., is Professor and Chair of Psychiatry at the University of Cape Town in South Africa and also has an affiliation with the University of Florida, Gainesville.

David J. Kupfer, M.D., is Thomas Detre Professor and Chair of the Department of Psychiatry at Western Psychiatric Institute and Clinic at the University of Pittsburgh in Pittsburgh, Pennsylvania.

Alan F. Schatzberg, M.D., is Kenneth T. Norris, Jr., Professor and Chairman in the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine in Stanford, California.

This is an overall and up-to-date review of all aspects of mood disorders, including epidemiology, pathophysiology, and clinical presentation as well as different treatment interventions, including psychotherapy. The book offers the latest science in the field and also guidance for proper diagnosis and treatment of mood disorders in daily practice. Not only should libraries have this book as a standard edition on their shelves, but also psychiatrists in the field should guide their practice [by consulting] the newest research in this textbook on mood disorders.—Siegfried Kasper, M.D., Professor and Chair, Department of General Psychiatry, Medical University of Vienna, Austria

This is a comprehensive book covering the state of progress on mood disorders, from the molecular biology to the day-to-day clinical aspects. Written and edited by internationally recognized clinician-researchers on mood disorders, it is an outstanding contribution to the field and will become a standard textbook in this important clinical domain. . . . It will surely become a benchmark for all other mood disorder textbooks. I highly recommend it!—Doody's Review Service, 1/1/2007

The present volume, massive and inclusive, representing the best efforts of knowledgeable colleagues, does not disappoint. Between the table of contents and the index, the clinician and/or investigator is certain to find up-to-date information on the desired topic.Every chapter contains data and ideas that add to one's understanding of mood-disordered patients, those at risk for such disorders, and those who should be patients but have not entered into a treatment relationship. Clearly, this textbook is a resource which no medical library and, ideally, no practitioner should be without.—The Journal of Nervous and Mental Disease, 1/1/2007

Until now, there had been no comprehensive text dealing with mood disorders that integrated basic research across the spectrum of mood disorders and offered clinical guidance based largely on empirical research. This need is well met by the publication of The American Psychiatric Publishing Textbook of Mood DisordersThis is an outstanding book, valuable as a desk reference for clinicians, psychologists, or psychiatrists as well as researchers interested in basic or clinical topics.—PsycCRITIQUES, 1/1/2007

This is a book that will stand the test of time. With eight section editors, whose names are household words throughout psychiatry, 99 highly qualified contributors to 43 chapters, and 778 pages, it is one big book. And why not? As the editors point out: Mood disorders are the bread and butter of clinical psychiatry: Just about everything you need to know about the subject is at your fingertips. The editing is excellent. The index is first-rate. Every chapter is referenced generously.If you want the most complete and timely text devoted entirely to mood disorders, this is the book for you. One would be hard pout to find a major omission that could not be explained by that unavoidable lag in publishing that is inherent in all books. I see its audience to be one with a clinical rather than basic research orientation, one that extends beyond psychiatry to a considerably wider range of mental health professionals (including those in primary care who are well immersed in recognizing, diagnosing, and treating disorders of mood).—American Journal of Psychiatry, 1/1/2007

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