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Handbook of Medicine in Psychiatry, Third Edition

Edited by Peter Manu, M.D., Corey Karlin-Zysman, M.D., and Eugene Grudnikoff, M.D.

  • ISBN 978-1-61537-228-7
  • Item #37228


Poverty, substandard medical care, social neglect or withdrawal, unhealthy lifestyle—these are just some of the contributors to the substantial morbidity of patients with severe mental illness. Medical deteriorations are often unexpected and severe, and particularly difficult to evaluate in the context of psychotic disorders.

For this new edition, the Handbook of Medicine in Psychiatry has been updated and streamlined to provide a realistic approach to the medical issues encountered in psychiatric practice by helpingclinicians answer whether their patient:

  • Is at risk of dying or becoming severely disabled.
  • Requires an immediate therapeutic intervention for a potentially life-threatening condition.
  • Needs to be transferred to an emergency medicine setting.
  • Requires urgent investigations.
  • Must have changes made in the current medication regimen.

Clinical vignettes for each chapter illustrate the complexity of the presentation of abnormal vital signs and somatic disorders in psychiatric settings, including fever, hypertension, seizures, and nausea and vomiting.

The guide also provides risk stratification for major complications—from abnormal thyroid function and acute kidney injury to myocarditis and venous thromboembolism—enabling readers to determine the need for a transfer of the patient to an emergency medicine setting.

A brand-new section features thorough discussions of topics requiring interdisciplinary collaboration with geriatricians, neurologists, anesthesiologists, addiction medicine,and adolescent medicine specialists.

Clinicians working in today’s busy inpatient and outpatient psychiatric settings will find in these pages a cognitive framework and knowledge base that will aid them in accurate decision making in the conditions of uncertainty created by potentially major medical deteriorations of the vulnerable populations under their care.



    Part I: Abnormal Vital Signs

    Chapter 1. Fever
    Chapter 2. Hypertension
    Chapter 3. Hypotension and Orthostasis
    Chapter 4. Abnormal Heart Rate

    Part II: Common Somatic Symptoms

    Chapter 5. Headache
    Chapter 6. Seizures
    Chapter 7. Falls and Head Trauma
    Chapter 8. Syncope and Unresponsiveness
    Chapter 9. Chest Pain
    Chapter 10. Shortness of Breath
    Chapter 11. Edema
    Chapter 12. Obstructive Sleep Apnea
    Chapter 13. Abdominal Pain and Heartburn
    Chapter 14. Nausea and Vomiting
    Chapter 15. Bowel Habit Changes
    Chapter 16. Dysuria, Incontinence, and Urinary Retention
    Chapter 17. Changes in Visual Acuity, Red Eye, and Eye Pain

    Part III: Abnormal Laboratory Findings

    Chapter 18. Glucose Dysregulation
    Chapter 19. Electrolyte Abnormalities
    Chapter 20. Abnormal Thyroid Function
    Chapter 21. Abnormal Liver Function
    Chapter 22. Acute Kidney Injury

    Part IV: Major Adverse Effects of Psychotropic Drugs

    Chapter 23. QTc Prolongation and Torsades de Pointes
    Chapter 24. Myocarditis and Cardiomyopathy
    Chapter 25. Neuroleptic Malignant Syndrome, Serotonin Syndrome, and Rhabdomyolysis
    Chapter 26. Neutropenia and Agranulocytosis
    Chapter 27. Venous Thromboembolism

    Part V: Interdisciplinary Interventions

    Chapter 28. Cardiopulmonary Emergencies
    Chapter 29. Agitation and Delirium
    Chapter 30. Adverse Events Associated With Electroconvulsive Therapy
    Chapter 31. Alcohol and Substance Abuse
    Chapter 32. Adolescent Medicine Topics for the Mental Health Practitioner
    Chapter 33. Geriatric Medicine Topics for the Mental Health Practitioner


    Esther Ahn, M.D.
    Adam Auerbach, M.D.
    Sandy Balwan, M.D., FACP
    Marigold Castillo, M.D.
    Jessica Cohen, M.D.
    Manjula Dhayalan, M.D.
    Sushmitha Echt, M.D.
    Ronald Feinstein, M.D.
    Julia Fernandez, M.D.
    Martin Fisher, M.D.
    Karen Friedman, M.D.
    James Gabriels, M.D.
    Marzena Gieniusz, M.D.
    Mark Goldin, M.D.
    Marc L. Gordon, M.D., FAAN
    Harly Greenberg, M.D.
    Eugene Grudnikoff, M.D.
    Kenneth Harris Jr., M.D.
    Farheen Hasan, M.D.
    Zubair Hasan, M.D.
    Chun Kit Hung, M.D.
    Sean T. Hwang, M.D.
    Annamaria Iakovou, M.D.
    Christopher Iamonaco, D.O.
    Fady Ibrahim, M.D.
    Nayla Idriss, M.D.
    Joji James, M.D.
    Patrick W. Joasil, M.D.
    Semie Kang, M.D.
    Imran Karim, M.D.
    Corey Karlin-Zysman, M.D., FHM, FACP
    Charles L. Kast, M.D.
    Kyle C. Katona, M.D.
    Courtney G. Kluger, M.D.
    Omid Kohani, M.D., FACC
    Linda M. Kurian, M.D.
    Nancy Kwon, M.D.
    Sean LaVine, M.D.
    Tai-Ping Lee, M.D.
    Katherine S. Lerner, M.D.
    Alexander Makhnevich, M.D.
    Peter Manu, M.D.
    Amy Mastrangelo, M.D.
    Joseph Mattana, M.D.
    Sassan Naderi, M.D.
    Chukwuemeka Obi, M.D.
    Margarita Oks, M.D.
    Rajvi Patel, M.D.
    Salonie Pereira, M.D.
    Aleksandra Polonetskaya, M.D.
    Simona V. Proteasa, M.D.
    David Purow, M.D.
    Mityanand Ramnarine, M.D.
    Sadia Riaz, M.D.
    Rifka Schulman-Rosenbaum, M.D.
    Sanjay Sekar, M.D.
    Hitesh H. Shah, M.D.
    Priyanka Singh, M.D.
    Liron Sinvani, M.D.
    Aren Skolnick, D.O.
    Philip Solomon, M.D.
    Nupur N. Uppal, M.D.
    Jessy Warner-Cohen, Ph.D.
    Gisele P. Wolf-Klein, M.D.
    Hai Xu, M.D.
    Deyun Yang, M.D., Ph.D.
    Warren D. Zysman, LCSW

About the Authors

Peter Manu, M.D. is Professor of Medicine and Psychiatry at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and Director of Medical Services, South Oaks Hospital in Amityville, New York.

Corey Karlin-Zysman, M.D. is Assistant Professor of Medicine at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and Associate Medical Director at Long Island Jewish Medical Center in New Hyde Park, New York.

Eugene Grudnikoff, M.D. is Assistant Professor of Psychiatry at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and Unit Chief, Child and Adolescent Psychiatry at Elmhurst Hospital, Elmhurst, New York.

This is the third edition of a seminal book first published in 2006. The first author, Peter Manu, a distinguished internal medicine specialist, has been imbedded in psychiatric programs as a key faculty member for several decades, actively participating in clinical and research activities. Professor Manu is also a leading national and international expert on functional somatic syndromes. The two other editors are psychiatrists, also based at Long island Jewish. The book includes 33 chapters, each chapter focusing on a specific medical issue that is quite relevant for patients suffering from mental disorders and particularly to professionals working in mental health settings. Each of these chapters has been neatly crafted and prepared by experts, and elegantly framed by the editors within a succinct, user-friendly, colorful format that includes a brief illustrative clinical vignette at the beginning of each chapter. The book nicely reflects a “commonsense approach” to these medical situations. It is clearly written and includes a list of essential references. The book is an essential addition to the work desks of practicing psychiatrists, psychologists and other mental health professionals.—Javier I Escobar M.D., M.Sc., Associate Dean for Global Health, Professor of Psychiatry and Family Medicine, Rutgers-Robert Wood Johnson Medical School

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